Autor:jmadunic

Autori: Sanja Milošević, Anica Bebek Markovinović, Nemanja Teslić, Aleksandra Mišan, Milica Pojić, Irena Brčić Karačonji, Karlo Jurica, Dario Lasić, Predrag Putnik, Danijela Bursać Kovačević, Branimir Pavlić Sažetak radaStrawberry tree fruits (Arbutus unedo L.) are being studied as an underutilized wild fruit, rich in various bioactive compounds, especially polyphenols. The main objective of this study was to optimize …
Nastavite čitati Use of natural deep eutectic solvent (NADES) as a green extraction of antioxidant polyphenols from strawberry tree fruit (Arbutus unedo L.): An optimization study

Autori: Goran Gajski, Elina Leonova, Nikolajs Sjakste Sažetak radaAmong the various natural compounds used in alternative and Oriental medicine, toxins isolated from different organisms have had their application for many years, and Apis mellifera venom has been studied the most extensively. Numerous studies dealing with the positive assets of bee venom (BV) indicated its beneficial properties. The usage …
Nastavite čitati Bee Venom: Composition and Anticancer Properties

Autori: Tamires Pavei Macan, Marina Lummertz Magenis, Adriani Paganini Damiani, Isadora de Oliveira Monteiro, Gustavo De Bem Silveira, Rubya Pereira Zaccaron, Paulo Cesar Lock Silveira, João Paulo Fernandes Teixeira, Goran Gajski, Vanessa Moraes de Andrade Sažetak radaType 2 diabetes mellitus (T2D) is a metabolic disease, which occurs largely due to unhealthy lifestyle. As oxidative stress is …
Nastavite čitati Brazil nut consumption reduces DNA damage in overweight type 2 diabetes mellitus patients

Autori: Buket Bakan, Nikolina Kalčec, Sijin Liu, Krunoslav Ilić, Yu Qi, Ivona Capjak, Lucija Božičević, Nikolina Peranić, Ivana Vinković Vrček Sažetak radaHuman exposure to plastic particles has raised great concern among all relevant stakeholders involved in the protection of human health due to the contamination of the food chain, surface waters, and even drinking water as …
Nastavite čitati Science-based evidence on pathways and effects of human exposure to micro- and nanoplastics

Autori: Dora Kolić, Zrinka Kovarik Sažetak radaAcute organophosphorus compound (OP) poisoning induces symptoms of the cholinergic crises with the occurrence of severe epileptic seizures. Seizures are induced by hyperstimulation of the cholinergic system, but are enhanced by hyperactivation of the glutamatergic system. Overstimulation of muscarinic cholinergic receptors by the elevated acetylcholine causes glutamatergic hyperexcitation and an …
Nastavite čitati N-methyl-d-aspartate receptors: Structure, function, and role in organophosphorus compound poisoning

Autori: Suzana Žunec, Donna Vadlja, Alma Ramić, Antonio Zandona, Nikola Maraković, Iva Brekalo, Ines Primožič, Maja Katalinić Sažetak radaThe cholinergic system, relying on the neurotransmitter acetylcholine (ACh), plays a significant role in muscle contraction, cognition, and autonomic nervous system regulation. The enzymes acetylcholinesterase, AChE, and butyrylcholinesterase, BChE, responsible for hydrolyzing ACh, can fine-tune the cholinergic system’s …
Nastavite čitati Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability

Autori: Andreja Jurič, Irena Brčić Karačonji, Suzana Žunec, Anja Katić, Uroš Gašic, Dušanka Milojković Opsenica, Nevenka Kopjar Sažetak radaStrawberry tree (Arbutus unedo L.) honey (STH) is widely used as part of traditional medicine in the Mediterranean area, especially in the treatment of wounds, burns and infections. In this study, we investigated the cyto-/genoprotective properties of STH at …
Nastavite čitati Protective role of strawberry tree (Arbutus unedo L.) honey against cyto/genotoxic effects induced by ultraviolet B radiation in vitro