{"id":616,"date":"2024-11-08T08:00:00","date_gmt":"2024-11-08T08:00:00","guid":{"rendered":"https:\/\/projekti.imi.hr\/biomoltox\/?p=616"},"modified":"2025-01-27T11:26:15","modified_gmt":"2025-01-27T11:26:15","slug":"domoic-acid-a-review-of-its-cytogenotoxicity-within-the-one-health-approach","status":"publish","type":"post","link":"https:\/\/projekti.imi.hr\/biomoltox\/2024\/11\/08\/domoic-acid-a-review-of-its-cytogenotoxicity-within-the-one-health-approach\/","title":{"rendered":"Domoic Acid: A Review of Its Cytogenotoxicity Within the One Health Approach"},"content":{"rendered":"\n<p><strong>Autori:<\/strong>\u00a0Goran Gajski, Marko Geri\u0107, Ana Bari\u010devi\u0107, Mirta Smodlaka Tankovi\u0107<\/p>\n\n\n\n<p><strong>Sa\u017eetak rada<\/strong><br>In this review, we toxicologically assessed the naturally occurring toxin domoic acid. We used the One Health approach because the impact of domoic acid is potentiated by climate change and water pollution on one side, and reflected in animal health, food security, human diet, and human health on the other. In a changing environment, algal blooms are more frequent. For domoic acid production, the growth of\u00a0<em>Pseudo-nitzschia<\/em>\u00a0diatoms is of particular interest. They produce this toxin, whose capability of accumulation and biomagnification through the food web impacts other organisms in the ecosystem. Domoic acid targets nervous system receptors inducing amnestic shellfish poisoning, among other less severe health-related problems. However, the impact of domoic acid on non-target cells is rather unknown, so we reviewed the currently available literature on cytogenetic effects on human and animal cells. The results of different studies indicate that domoic acid has the potential to induce early molecular events, such as oxidative imbalance and DNA damage, thus posing an additional threat which needs to be thoroughly addressed and monitored in the future.<\/p>\n\n\n\n<p>Rad je dostupan na sljede\u0107oj\u00a0<a href=\"https:\/\/www.mdpi.com\/2076-3921\/13\/11\/1366\" data-type=\"link\" data-id=\"https:\/\/www.mdpi.com\/2076-3921\/13\/11\/1366\" target=\"_blank\" rel=\"noreferrer noopener\">poveznici<\/a>.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Autori:\u00a0Goran Gajski, Marko Geri\u0107, Ana Bari\u010devi\u0107, Mirta Smodlaka Tankovi\u0107 Sa\u017eetak radaIn this review, we toxicologically assessed the naturally occurring toxin domoic acid. We used the One Health approach because the impact of domoic acid is potentiated by climate change and water pollution on one side, and reflected in animal health, food security, human diet, and &hellip;<br \/><a href=\"https:\/\/projekti.imi.hr\/biomoltox\/2024\/11\/08\/domoic-acid-a-review-of-its-cytogenotoxicity-within-the-one-health-approach\/\" class=\"more-link pen_button pen_element_default pen_icon_arrow_double\">Continue reading <span class=\"screen-reader-text\">Domoic Acid: A Review of Its Cytogenotoxicity Within the One Health Approach<\/span><\/a><\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13],"tags":[],"class_list":["post-616","post","type-post","status-publish","format-standard","hentry","category-pub-hr"],"acf":[],"_links":{"self":[{"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/posts\/616","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/comments?post=616"}],"version-history":[{"count":1,"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/posts\/616\/revisions"}],"predecessor-version":[{"id":618,"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/posts\/616\/revisions\/618"}],"wp:attachment":[{"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/media?parent=616"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/categories?post=616"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/projekti.imi.hr\/biomoltox\/wp-json\/wp\/v2\/tags?post=616"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}