Category:Publications

Authors: Dora Kolić, Goran Šinko, Ludovic Jean, Mourad Chioua, José Dias, José Marco-Contelles, Zrinka Kovarik Abstract Olesoxime, a cholesterol derivative with an oxime group, possesses the ability to cross the blood-brain barrier and has demonstrated excellent safety and tolerability properties in clinical research. These characteristics indicate it may serve as a centrally active ligand of …
Continue reading Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases

Authors: Carina Ladeira, Peter Møller, Lisa Giovannelli, Goran Gajski, Anja Haveric, Ezgi Eyluel Bankoglu, Amaya Azqueta, Marko Gerić, Helga Stopper, José Cabêda, Fernanda S Tonin, Andrew Collins AbstractBiomonitoring of human populations exposed to chemical substances that can act as potential mutagens or carcinogens, may enable the detection of damage and early disease prevention. In recent years, …
Continue reading The Comet Assay as a Tool in Human Biomonitoring Studies of Environmental and Occupational Exposure to Chemicals—A Systematic Scoping Review

Authors: Davor Želježić, Goran Kovačević, Ana Matijević, Petra Korać, Katarina Caput Mihalić AbstractThe aim of this paper was to evaluate whether symbiotic cooperation between green hydra (Hydra viridissima) and photoautotrophic alga gives higher resistance of the preservation of DNA integrity compared to brown hydra (Hydra oligactis). Norflurazon concentrations were 0.061 or 0.61 mg/L and UV-B light 254 nm, …
Continue reading Does the Symbiotic Relationship Between Hydra Viridissima and Photoautotrophic Alga Provide an Evolutionary Advantage in Protecting DNA against Damage by the Cytotoxic or Genotoxic Mode of Action of Environmental Stressors?

Authors: Dora Kolić, Vesna Pehar, Zrinka Kovarik AbstractGlyphosate has remained the leading herbicide on the global market to date, despite the continuous debate between consumers, scientific community, and regulatory agencies over its carcinogenicity, genotoxicity, environmental persistence, and the role in the development of neurodegenerative disorders. Chemically, glyphosate belongs to a large family of organophosphorus pesticides, which …
Continue reading Environmental exposure to glyphosate does not inhibit human acetylcholinesterase and butyrylcholinesterase

Authors: Goran Gajski, Vilena Kašuba, Mirta Milić, Marko Gerić, Katarina Matković, Luka Delić, Maja Nikolić, Martina Pavičić, Ružica Rozgaj, Vera Garaj-Vrhovac, Nevenka Kopjar AbstractIn this study, we used the cytokinesis-block micronucleus (CBMN) assay to evaluate the background frequency of cytogenetic damage in peripheral blood lymphocytes of the general population concerning different anthropometric data and lifestyle factors. …
Continue reading Exploring cytokinesis block micronucleus assay in Croatia: A journey through the past, present, and future in biomonitoring of the general population

Authors: Marko Gerić, Gordana Pehnec, Katarina Matković, Jasmina Rinkovec, Ivana Jakovljević, Ranka Godec, Silva Žužul, Ivan Bešlić, Ante Cvitković, Luka Delić, Pascal Wild, Irina Guseva Canu, Nancy B Hopf, Goran Gajski AbstractMore than eight million premature deaths annually can be attributed to air pollution, with 99% of the world’s population residing in areas below recommended air …
Continue reading Air Pollution and Primary DNA Damage among Zagreb (Croatia) Residents: A Cross-Sectional Study

Authors: Sanja Milošević, Anica Bebek Markovinović, Nemanja Teslić, Aleksandra Mišan, Milica Pojić, Irena Brčić Karačonji, Karlo Jurica, Dario Lasić, Predrag Putnik, Danijela Bursać Kovačević, Branimir Pavlić AbstractStrawberry tree fruits (Arbutus unedo L.) are being studied as an underutilized wild fruit, rich in various bioactive compounds, especially polyphenols. The main objective of this study was to optimize the …
Continue reading Use of natural deep eutectic solvent (NADES) as a green extraction of antioxidant polyphenols from strawberry tree fruit (Arbutus unedo L.): An optimization study

Authors: Goran Gajski, Elina Leonova, Nikolajs Sjakste AbstractAmong the various natural compounds used in alternative and Oriental medicine, toxins isolated from different organisms have had their application for many years, and Apis mellifera venom has been studied the most extensively. Numerous studies dealing with the positive assets of bee venom (BV) indicated its beneficial properties. The usage of …
Continue reading Bee Venom: Composition and Anticancer Properties

Authors: Goran Kovačević, Ana Matijević, Petra Korać, Davor Želježić, Siegfried Reipert, Katarina Caput Mihalić, Damir Sirovina, Petra Peharec Štefanić, Martina Ivšić AbstractIn this study, we aimed to document the freshwater symbiotic interactions along with the impact of the abiotic environment and anthropogenic effects on the functionality of freshwater organisms. Symbiotic green hydra (Z) and free-living brown …
Continue reading Effects of Norflurazon and UV Radiation on Symbiotic and Free-Living Hydra