Authors: Buket Bakan, Nikolina Kalčec, Sijin Liu, Krunoslav Ilić, Yu Qi, Ivona Capjak, Lucija Božičević, Nikolina Peranić, Ivana Vinković Vrček AbstractHuman exposure to plastic particles has raised great concern among all relevant stakeholders involved in the protection of human health due to the contamination of the food chain, surface waters, and even drinking water as well …
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Category:Publications
N-methyl-d-aspartate receptors: Structure, function, and role in organophosphorus compound poisoning
Authors: Dora Kolić, Zrinka Kovarik AbstractAcute organophosphorus compound (OP) poisoning induces symptoms of the cholinergic crises with the occurrence of severe epileptic seizures. Seizures are induced by hyperstimulation of the cholinergic system, but are enhanced by hyperactivation of the glutamatergic system. Overstimulation of muscarinic cholinergic receptors by the elevated acetylcholine causes glutamatergic hyperexcitation and an increased …
Continue reading N-methyl-d-aspartate receptors: Structure, function, and role in organophosphorus compound poisoning
Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability
Authors: Suzana Žunec, Donna Vadlja, Alma Ramić, Antonio Zandona, Nikola Maraković, Iva Brekalo, Ines Primožič, Maja Katalinić AbstractThe cholinergic system, relying on the neurotransmitter acetylcholine (ACh), plays a significant role in muscle contraction, cognition, and autonomic nervous system regulation. The enzymes acetylcholinesterase, AChE, and butyrylcholinesterase, BChE, responsible for hydrolyzing ACh, can fine-tune the cholinergic system’s activity …
Continue reading Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability
Protective role of strawberry tree (Arbutus unedo L.) honey against cyto/genotoxic effects induced by ultraviolet B radiation in vitro
Authors: Andreja Jurič, Irena Brčić Karačonji, Suzana Žunec, Anja Katić, Uroš Gašic, Dušanka Milojković Opsenica, Nevenka Kopjar AbstractStrawberry tree (Arbutus unedo L.) honey (STH) is widely used as part of traditional medicine in the Mediterranean area, especially in the treatment of wounds, burns and infections. In this study, we investigated the cyto-/genoprotective properties of STH at cell …
Continue reading Protective role of strawberry tree (Arbutus unedo L.) honey against cyto/genotoxic effects induced by ultraviolet B radiation in vitro