Category:Publications

Authors: Tena Čadež, Nikolina Maček Hrvat, Goran Šinko, Jarosław Kalisiak, Zoran Radić, Valery V. Fokin, Karl Barry Sharpless, Palmer Taylor, Zrinka Kovarik AbstractA library of 100 click-chemistry-derived oximes was evaluated as reactivators of butyrylcholinesterase (BChE) inhibited by the nerve agents (NAs) sarin, cyclosarin, VX, and tabun. While reactivation efficiency was highly dependent on the structure of …
Continue reading Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging

Authors: Irena Brčić Karačonji, Tea Jelača, Andreja Jurič, Ana Lucić Vrdoljak AbstractOpiates such as morphine and codeine are substances often misused to improve the performance of racing horses during competitions and are therefore on the International Federation for Equestrian Sports’ list of prohibited substances. However, a positive antidoping test may be due to the consumption of …
Continue reading Morphine and codeine in racing horse feed: is there reason for concern?

Authors: Ana Barbarić, Lara Saftić Martinović, Danijel D. Milinčić, Mirjana B. Pešić, Zvonimir Marijanović, Mateo Jakac, Irena Brčić Karačonji, Helena Brekalo, Danijela Petrović, Tomislav Pavlešić, Dijana Mišetić Ostojić, Ivana Gobin AbstractThis study compares beech (Fagus sylvatica) and chestnut (Castanea sativa) honeydew honeys through analyses of physicochemical properties, pollen composition, phenolic and volatile compounds, and bioactivity. Beech …
Continue reading Characterization and differentiation of beech and chestnut honeydew honeys: A comparative study

Authors: Ivana Jakovljević, Zdravka Sever Štrukil, Gordana Pehnec, Tajana Horvat, Mandica Sanković, Antun Šumanovac, Silvije Davila, Nikolina Račić, Goran Gajski AbstractMeasurements of polycyclic aromatic hydrocarbons (PAHs) were simultaneously carried out at three different urban locations in Croatia (Zagreb, Slavonski Brod and Vinkovci) characterized as urban residential (UR), urban industrial (UI) and urban background (UB), respectively. This …
Continue reading Ambient air pollution and carcinogenic activity at three different urban locations

Authors: Dražen Lušić, Sara Beza, Irena Brčić Karačonji AbstractCaffeine is a natural stimulant of plant origin found in many products such as coffee, tea, chocolate, and energy drinks. It is also often used as an active substance in over-the-counter drugs such as painkillers and preparations for the treatment of colds and allergies. While caffeine is generally …
Continue reading What is more common in fatal caffeine intoxication – suicide or unintentional overdose?

Authors: Mirta Milić, Luka Kazensky, Martina Matovinović AbstractThe prevalence of metabolic syndrome (MetS) worldwide is rapid and significant on a global scale. A 2022 meta-analysis of data from 28 million individuals revealed a global prevalence of 45.1%, with notably higher rates in the Eastern Mediterranean Region and the Americas, particularly in high-income countries. MetS is associated …
Continue reading The Impact of the Metabolic Syndrome Severity on the Appearance of Primary and Permanent DNA Damage

Authors: Katarina Matković, Andreja Jurič, Ivana Jakovljević, Luka Kazensky, Mirta Milić, Vilena Kašuba, Silvije Davila, Gordana Pehnec, Irena Brčić Karačonji, Ante Cvitković, Pascal Wild, Irina Guseva Canu, Nancy B. Hopf, Goran Gajski, Marko Gerić AbstractAir pollution, a major global issue, comprises various solid and gaseous pollutants in urban environments, including particulate matter (PM) and volatile organic …
Continue reading Evaluating air pollution and BTEX exposure effects on DNA damage: A human biomonitoring study in Zagreb, Croatia

Authors: Dubravka Rašić, Antonio Zandona, Maja Katalinić, Martin Češi, Nevenka Kopjar AbstractThe increasing use of Cannabis sativa products for medicinal, dietary, and recreational purposes has raised concerns about mycotoxin contamination in cannabis and hemp. Mycotoxins persist in these products’ post-processing, posing health risks via multiple exposure routes. This study investigated cytotoxic and genotoxic interactions between cannabidiol (CBD) and …
Continue reading Assessing the Potential Synergistic/Antagonistic Effects of Citrinin and Cannabidiol on SH-SY5Y, HepG2, HEK293 Cell Lines, and Human Lymphocytes

Authors: Maja Lazarus, Agnieszka Sergiel, Tatjana Orct, Maja Ferenčaković, Blanka Tariba Lovaković, Suzana Žunec, Dubravka Rašić, Ena Oster, Slaven Reljić, Joanna Macur, Đuro Huber AbstractInduction of oxidative stress and the associated lipid peroxidation is a prevalent mechanism through which certain metal(loid)s exert nephrotoxic effects in mammals. Research on the toxic impacts of metal(loid)s in free-ranging large …
Continue reading Apex carnivores coping with metal(loid) pollution and oxidative stress: Biological and environmental drivers of variation in kidney of European brown bear