Autori: Goran Gajski, Marko Gerić, Ana Baričević, Mirta Smodlaka Tanković Sažetak radaIn this review, we toxicologically assessed the naturally occurring toxin domoic acid. We used the One Health approach because the impact of domoic acid is potentiated by climate change and water pollution on one side, and reflected in animal health, food security, human diet, and …
Nastavite čitati Domoic Acid: A Review of Its Cytogenotoxicity Within the One Health Approach
Kategorija:Publikacije
Combinatory Effect of Nitroxoline and Gentamicin in the Control of Uropathogenic Enterococci Infections
Autori: Davorka Repac Antić, Bruno Kovač, Marko Kolenc, Irena Brčić Karačonji, Ivana Gobin, Mirna Petković Didović Sažetak radaEnterococcus faecalis, responsible for a majority of human and nosocomial enterococcal infections, is intrinsically resistant to aminoglycoside antibiotics (such as gentamicin, GEN), which must be used in a combined therapy to be effective. Nitroxoline (NTX) is an old …
Nastavite čitati Combinatory Effect of Nitroxoline and Gentamicin in the Control of Uropathogenic Enterococci Infections
Effects of Strawberry Tree (Arbutus unedo L.) Aqueous Leaf Extract and Arbutin on PK-15 and HepG2 Cells
Autori: Vesna Benković*, Ines Tkalčec, Anica Knežević, Karlo Jurica, Fabijan Knežević, Irena Brčić Karačonji, Nevenka Kopjar Sažetak radaThe antioxidant properties of the leaves of the Mediterranean strawberry tree (Arbutus unedo L.) are mainly attributed to the main bioactive compound, the phenolic glycoside arbutin. In this study, the safety profile of strawberry tree aqueous leaf extract (STE) …
Nastavite čitati Effects of Strawberry Tree (Arbutus unedo L.) Aqueous Leaf Extract and Arbutin on PK-15 and HepG2 Cells
Effects of Strawberry Tree Water Leaf Extract and Arbutin on Biochemical Markers and DNA Integrity in Brain Cells of Lewis Rats
Autori: Vesna Benković*, Dora Vuković, Iva Đelatić, Vanja Popović, Karlo Jurica, Fabijan Knežević, Irena Brčić Karačonji, Ana Lucić Vrdoljak, Nevenka Kopjar Sažetak radaThere is growing evidence that arbutin and plant extracts rich in arbutin, such as extracts of the strawberry tree (Arbutus unedo L.), exert a range of beneficial effects, including cyto- and genoprotective properties. This …
Nastavite čitati Effects of Strawberry Tree Water Leaf Extract and Arbutin on Biochemical Markers and DNA Integrity in Brain Cells of Lewis Rats
Hydra for 21st Century—A Fine Model in Freshwater Research
Autori: Goran Kovačević, Petra Korać, Davor Želježić, Mirela Sertić Perić, Petra Peharec Štefanić, Damir Sirovina, Maja Novosel, Sanja Gottstein Sažetak radaHydra is known for its natural occurrence, anatomical simplicity, intricate physiology, regenerative capacity, and ease of maintenance and manipulation in laboratory environments. It has proven to be a valuable model organism in various disciplines. Its applications range …
Nastavite čitati Hydra for 21st Century—A Fine Model in Freshwater Research
Comparison of DNA damage in fresh and frozen blood samples: implications for the comet assay in human biomonitoring studies
Autori: Katarina Matković, Marko Gerić, Luka Kazensky, Mirta Milić, Vilena Kašuba, Ante Cvitković, Mandica Sanković, Antun Šumanovac, Peter Møller, Goran Gajski Sažetak radaThe use of the comet assay in large biomonitoring studies may present logistical and technical challenges because of the processing of numerous samples. Proper sample preservation becomes imperative to prevent spurious DNA breakage. Previous …
Nastavite čitati Comparison of DNA damage in fresh and frozen blood samples: implications for the comet assay in human biomonitoring studies
New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics
Autori: Milena Mlakić, Tena Čadež, Goran Šinko, Irena Škorić, Zrinka Kovarik Sažetak radaNew furan, thiophene, and triazole oximes were synthesized through several-step reaction paths to investigate their potential for the development of central nervous systems (CNS)-active and cholinesterase-targeted therapeutics in organophosphorus compound (OP) poisonings. Treating patients with acute OP poisoning is still a challenge despite the …
Nastavite čitati New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics
Evaluation of Anticholinesterase Activity of the Fungicides Mefentrifluconazole and Pyraclostrobin
Autori: Dora Kolić, Goran Šinko Sažetak radaTriazoles are compounds with various biological activities, including fungicidal action. They became popular through cholinesterase studies after the successful synthesis of the dual binding femtomolar triazole inhibitor of acetylcholinesterase (AChE, EC 3.1.1.7) by Sharpless et al. via in situ click chemistry. Here, we evaluate the anticholinesterase effect of the first isopropanol triazole …
Nastavite čitati Evaluation of Anticholinesterase Activity of the Fungicides Mefentrifluconazole and Pyraclostrobin
Impact of indoor air pollution on DNA damage and chromosome stability: a systematic review
Autori: Luka Kazensky, Katarina Matković, Marko Gerić, Bojana Žegura, Gordana Pehnec, Goran Gajski Sažetak radaIndoor air pollution is becoming a rising public health problem and is largely resulting from the burning of solid fuels and heating in households. Burning these fuels produces harmful compounds, such as particulate matter regarded as a major health risk, particularly affecting …
Nastavite čitati Impact of indoor air pollution on DNA damage and chromosome stability: a systematic review