Autori: Marko Gerić, Lucia Nanić, Vedran Micek, Ivana Novak Jovanović, Goran Gajski, Dubravka Rašić, Tatjana Orct, Marija Ljubojević, Dean Karaica, Jasna Jurasović, Ivana Vrhovac Madunić, Maja Peraica, Ivan Sabolić, Vanessa Moraes de Andrade, Davorka Breljak, Ivica Rubelj Sažetak radaBackground: Given the growing challenges posed by an ageing population, particularly in Western countries, we aimed to investigate …
Nastavite čitati The Impact of Resveratrol and Melatonin on the Genome and Oxidative Status in Ageing Rats
Autor:jmadunic
Preliminary Insights into the Cyto/Genoprotective Properties of Propolis and Its Constituent Galangin In Vitro
Autori: Mateo Jakac, Irena Brčić Karačonji, Andreja Jurič, Dražen Lušić, Danijel Milinčić, Aleksandra Dramićanin, Mirjana Pešić, Nediljko Landeka, Nevenka Kopjar Sažetak radaPropolis has been well known for centuries as a natural preventive and therapeutic agent. Its numerous health benefits are mainly attributed to its high content of phenolic compounds that have a remarkable antioxidant activity. Since …
Nastavite čitati Preliminary Insights into the Cyto/Genoprotective Properties of Propolis and Its Constituent Galangin In Vitro
Znanstvena suradnja s dvostrukim nobelovcem K. Barryjem Sharplessom
Djelatnici našeg Instituta, u suradnji s dvostrukim dobitnikom Nobelove nagrade iz kemije K. Barryjem Sharplessom, objavili su rad u vrhunskom časopisu Archieves of Toxicology: Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging Rad je nastavak dugogodišnje suradnje s kalifornijskim znanstvenicima s University of California at San Diego i The …
Nastavite čitati Znanstvena suradnja s dvostrukim nobelovcem K. Barryjem Sharplessom
Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging
Autori: Tena Čadež, Nikolina Maček Hrvat, Goran Šinko, Jarosław Kalisiak, Zoran Radić, Valery V. Fokin, Karl Barry Sharpless, Palmer Taylor, Zrinka Kovarik Sažetak radaA library of 100 click-chemistry-derived oximes was evaluated as reactivators of butyrylcholinesterase (BChE) inhibited by the nerve agents (NAs) sarin, cyclosarin, VX, and tabun. While reactivation efficiency was highly dependent on the structure …
Nastavite čitati Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging
Morphine and codeine in racing horse feed: is there reason for concern?
Autori: Irena Brčić Karačonji, Tea Jelača, Andreja Jurič, Ana Lucić Vrdoljak Sažetak radaOpiates such as morphine and codeine are substances often misused to improve the performance of racing horses during competitions and are therefore on the International Federation for Equestrian Sports’ list of prohibited substances. However, a positive antidoping test may be due to the consumption …
Nastavite čitati Morphine and codeine in racing horse feed: is there reason for concern?
Characterization and differentiation of beech and chestnut honeydewhoneys: A comparative study
Autori: Ana Barbarić, Lara Saftić Martinović, Danijel D. Milinčić, Mirjana B. Pešić, Zvonimir Marijanović, Mateo Jakac, Irena Brčić Karačonji, Helena Brekalo, Danijela Petrović, Tomislav Pavlešić, Dijana Mišetić Ostojić, Ivana Gobin Sažetak radaThis study compares beech (Fagus sylvatica) and chestnut (Castanea sativa) honeydew honeys through analyses of physicochemical properties, pollen composition, phenolic and volatile compounds, and bioactivity. …
Nastavite čitati Characterization and differentiation of beech and chestnut honeydewhoneys: A comparative study
Ambient air pollution and carcinogenic activity at three different urban locations
Autori: Ivana Jakovljević, Zdravka Sever Štrukil, Gordana Pehnec, Tajana Horvat, Mandica Sanković, Antun Šumanovac, Silvije Davila, Nikolina Račić, Goran Gajski Sažetak radaMeasurements of polycyclic aromatic hydrocarbons (PAHs) were simultaneously carried out at three different urban locations in Croatia (Zagreb, Slavonski Brod and Vinkovci) characterized as urban residential (UR), urban industrial (UI) and urban background (UB), respectively. …
Nastavite čitati Ambient air pollution and carcinogenic activity at three different urban locations
What is more common in fatal caffeine intoxication – suicide or unintentional overdose?
Autori: Dražen Lušić, Sara Beza, Irena Brčić Karačonji Sažetak radaCaffeine is a natural stimulant of plant origin found in many products such as coffee, tea, chocolate, and energy drinks. It is also often used as an active substance in over-the-counter drugs such as painkillers and preparations for the treatment of colds and allergies. While caffeine is …
Nastavite čitati What is more common in fatal caffeine intoxication – suicide or unintentional overdose?
The Impact of the Metabolic Syndrome Severity on the Appearance of Primary and Permanent DNA Damage
Autori: Mirta Milić, Luka Kazensky, Martina Matovinović Sažetak radaThe prevalence of metabolic syndrome (MetS) worldwide is rapid and significant on a global scale. A 2022 meta-analysis of data from 28 million individuals revealed a global prevalence of 45.1%, with notably higher rates in the Eastern Mediterranean Region and the Americas, particularly in high-income countries. MetS is …
Nastavite čitati The Impact of the Metabolic Syndrome Severity on the Appearance of Primary and Permanent DNA Damage